CellChek SL

The global golden standard in endothelial analytics

CellChek Clinical Benefits

Cataract Surgery and Premium IOLs

Low endothelial cell counts and pre-existing dystrophies can markedly reduce the potential for positive surgical outcomes from an otherwise uneventful cataract surgery. Surgeons are finding these data points critical when recommending premium IOLs: verify and document pre-operatively that the cornea is not suspect to more likely post-op complications difficult to explain with the investment in premium IOLs.

Refractive Surgery

There are various reports in the literature of refractive surgery complications with corneas that have pre-existing dystrophies. It is incumbent on refractive surgeons and referring Optometrists to carefully assess the corneal health prior to performing or recommending an elective corneal surgery to enhance the potential for positive surgical outcomes.

General Corneal Health Assessment

Konan specular microscopy is an invaluable tool to screen for corneal diseases as such as Fuchs’ Dystrophy, keratoconus, other corneal dystrophies, and trauma. You won’t believe what you’ve been missing.

Contact Lenses

In the never ending battle to minimize the oxygen barrier from contact lens materials and lens hygiene, specular microscopy provides a highly detailed view of the integrity and distress of the cornea from the endothelium. As the “canary in the coal mine”, the endothelium can be an invaluable indicator of corneal distress.

Konan Cellcheck SL
Shaffer Vision Solutions
Shaffer Vision Solutions
Shaffer Vision Solutions
Shaffer Vision Solutions

It is not a coincidence...

… that virtually every manufacturer of pharmaceutical agents and implantable devices that are required by the FDA to collect endothelial density as a primary safety endpoint, have had their clinical research teams, completely independently, assess the specular microscopes available on the market and have chosen Konan. Repeatedly.


Cutting edge technology in a compact, portable device with extremely low operating costs

EvokeDx is the next generation icVEP + VEP + ERG device developed by Konan Medical and leading scientists in visual electrophysiology.  Its compact, all-in-one form factor features numerous market-leading technologies including:  intuitive touch-screen user interface Organic LED stimulus display, infrared gaze and attention monitoring dual-channel amplifier, and powerful Fourier (Frequency domain) analytics with intuitive reporting. EvokeDx is a fresh approach to visual electrophysiology.

EvokeDx Clinical Benefits

Visual Evoked Potentials (VEP) provide objective, quantitative information about the functional integrity of discrete visual pathways in a non-invasive manner. This is new information that is complementary to the structural analysis obtained from technologies such as OCT and Fundus photography, and augments subjective information from standard visual acuity and perimetry. Electroretinograms (ERG) reflect the integrity of the optics, photoreceptors, bipolar cells and retinal ganglion cells. Clinically, ERGs may be useful when patients have abnormal VEPs to differentiate between retinal dysfunction occurring in the optic nerve, optic radiations and occipital cortex.

Operator Aspect

The Operator side of EvokeDx features an intuitive, touch-screen enabled user experience graphically guiding the operator easily through the test sequence:

  • patient add | select
  • test select
  • patient alignment
  • testing
  • results / analytics
  • preferences / settings

Analytics instantly displays test results and Fourier analytics. One-touch help screens provide context-sensitive explanations of all analytic components for all tests. A robust comparison feature allows instant comparisons. For example:

  • compare right and left eyes on same day
  • compare same eye from a prior exam to assess progression
  • compare how a bright response compares to dark response, same pattern
  • compare how a small check response compares to large check response
  • compare how one patient compares to another patient of known characteristics
Operator Aspect

Patient Aspect

The patient side of EvokeDx features a high specification OLED stimulus display, patient gaze / attention tracking, and easy plug-in for electrodes to internal dual-channel amplifier. Say goodbye to asking the patient to hold a single-channel amplifier!

Patient Aspect


Checking pupils for RAPDs is an important part of the comprehensive eye exam and is recommended in the AAO’s Preferred Practice Patterns® for POAG suspects and patients however the swinging flashlight test is difficult for humans to do well, and even more difficult and time consuming to accurately quantify.

Importantly, there is evidence that very small RAPDs may be clinically significant.


Enter EyeKinetix

EyeKinetix utilizes a high-definition, machine-vision system under controlled infrared conditions to present monocular visual stimuli while recording binocular pupil responses. Unlike human observers that only see one eye response at a time, EyeKinetix simultaneous images both direct and consensual light responses. The power of the system is to collect a series of responses and average them into a consolidated response curve. Pupil testing is notoriously non-standardized, variable, and noisy. Response averaging significantly helps filter the noise inherent in the biological responses.

Easy, objective, quantitative, delegated, detailed … perhaps better than the finest human observer. EyeKinetix may be the most significant advancement in pupil testing in decades.


Objective perimetry has long been desired. Now, with more than 12 years research and over 17,000 exams performed, Konan introduces the objectiveFIELD analyzer (OFA®).  Estimated availability Q4 2019.

The objectiveFIELD™ analyzer, the OFA®, features a novel, multi-focal stimulus for objective visual field testing in which both eyes are tested simultaneously, without requiring the patient to press a response button.

The most disliked ophthalmic diagnostic test has evolved.

Konan’s OFA is FDA 510(k) Cleared and CE MARK activities have been initiated. More information is coming soon.

OFA patients

ColorDx® CCT-HD™

FDA listed | CPT CODE 92283 | CE Marked

Developed by and licensed to Konan Medical in collaboration with the United States Air Force School of Aerospace Medicine OBVA (Operational Based Vision Assessment) laboratory under CRADA, CCT-HD represents the new gold standard for color vision diagnostics.

Featuring the robust Psi-marginal method for threshold determination, CCT-HD expands on the strengths of the original cone contrast test (CCT) built from the ground up with entirely new architecture, highlights include:

  • Cone-Isolation contrast methodology
  • “Landolt C” based test strategies
  • Simple to use 4-button response pad
  • Robust thresholding and standard error
  • Konan custom-calibrated IPS display technology
  • Rapid, intuitive, staged calibration
  • Expanded low-contrast range testing
  • High fidelity cone-contrast granularity
  • Expansive illustrated reporting
  • Auto trends analysis
  • Contrast Sensitivity (achromatic) with auto AUC calculation
    (Coming Soon!)

Clinical Benefits of Diagnostic Color Vision Testing

Tritan (S-cone or blue-yellow type) deficiencies are rarely genetic, yet may affect up to 15%* of the general population. Acquired deficiencies are commonly S-cone type, but may also affect L and M-cones. Acquired deficiencies are gender neutral and become more common with age.
This important but often overlooked clinical sign may be caused by retinal, optic nerve, trauma or neurological disorders, in addition to cataracts and high-risk meds, as well as hundreds of common drugs and substances**.This important but often overlooked clinical sign may be caused by retinal, optic nerve, trauma or neurological disorders, in addition to cataracts and high-risk meds, as well as hundreds of common drugs and substances**.
High-definition, cone-isolation contrast testing provides a detailed assessment (with a numeric score) of each cone-cell population. The contrast “Threshold” scores as well as associated “Standard Error”, are useful to quantify performance as well as for assessing changes over time from acquired deficiencies that have been otherwise clinically missed entirely.

Konan Colordx

Testing for acquired color vision deficiencies may be one of the most underutilized measures of functional vision. Commonly used color vision tests (such as printed pseudo-isochromatic “Ishihara plates” designed a century ago), may only test genetic L and M-cone deficiencies, completely missing all S-cone (blue) deficiencies as well as being not quantitative.
Contemporary eyecare includes qualitative and quantitative assessment of this important measure of functional vision. ColorDx CCT-HD is the state-of-the-art system to assess color vision deficiencies in high-definition.
*Rayman, R., et al. Rayman’s Clinical Aviation Medicine. Castle Connelly. 2013.
**Fraunfelder, Fraunfelder, Chambers. Clinical Ocular Toxicology. Sanders Elsevier, 2008: 320. Clinical Ocular Toxicology, Substances and Pharmaceutical Agents that can Cause Color Vision Defects.

ColorDx Clinical Resources