BioDOptix

Clearly Focused On Improving Vision

BioDOptix® is a dehydrated, extracellular membrane allograft derived from human amniotic tissue that is intended for homologous use as a scaffold for ocular tissue repair.

Performance

• Dehydrated using our proprietary DryFlex® process that preserves the inherent extracellular matrix, growth factors, and cytokines of the amniotic tissue
• Easy to apply and conforms well to the anterior ocular surface
• Placement generally does not require sutures or glue

BioDOptix

Convenience

• Circular or rectangular sizes for appropriate fit.
• Dehydrated product allows for easy trim-to-size fitting
• Room temperature storage with 5 year shelf life
• Convenient for use in inpatient, outpatient or clinic settings

Confidence

• Amniotic tissues have been described as immune-privileged because they rarely evoke an immune response in the human body1
• Tissue recovered from live, healthy donors during cesarean childbirth
• Donor selection, tissue recovery and processing protocols and procedures meet or exceed all applicable industry standards to ensure patient safety

BioDOptix

• Amniotic extracellular matrix composition of collagen, elastin, fibronectin and proteoglycans provides a natural scaffold to facilitate cellular adhesion while assisting cellular migration and proliferation.2

• Amniotic tissue has been shown to help reduce inflammation and pain, scar tissue formation, and the risk of infection.2, 3

Common Clinical Applications of Amniotic Tissues

  • Ocular Surface Disorders
  • Corneal Epithelial Defects
  • Corneal Ulcer
  • Adjunctive Therapy for PK Cornea Transplant
  • Pterygium
  • Band Keratopathy
  • Bullous Keratopathy

BioDOptix

  • OX-010152 – 1.5 x 2.0cm2
  • OX-010203 – 2.0 x 3.0cm2
  • OX-010009 – 9.0mm disc
  • OX-010012 – 12.0mm disc
  • OX-010015 – 15.0mm disc

References

1. Kubo, et al. Immunogenicity of Human Amniotic Membrane in Experimental Xenotransplantation. Investigative Ophthalmology & Visual Science, June 2001, Vol. 42, No. 7.
2. Niknejad, H, et al. Properties of amniotic membrane for potential use in Tissue Engineering. European Cells and Materials 2008; Vol 15: 88-99.
3. Gruss, J, et al. Human amniotic membrane: a versatile wound dressing. CMA Journal 1978; Vol 118: 1237-1246.

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